A biotech company in Madison, Wisconsin believes a protein from a jellyfish (with the scientific name, Aequorea victoria) can improve cognitive function in people with memory problems, Alzheimer’s disease or other dementias.
Quincy Bioscience representatives are at the annual Alzheimer’s Association International Conference on Alzheimer’s Disease this week in Honolulu, presenting interim data that demonstrates the jellyfish protein improved cognitive testing scores by 14 percent in 60 days compared to placebo in the randomized controlled “Madison Memory Study,” which enrolled adults who had a memory concern. The average age in the study cohort of 35 people was 61 years old.
Why the jellyfish?
Partly because of its simplicity. “If you strip down all of the higher functions of thought from the human brain, you really end up with a very simple nervous system…as simple as the jellyfish,” says the Quincy website. Scientists have been studying the design of the jellyfish to understand how it might protect brain cells. Jellyfish make use of apoaequorin to sequester extra calcium ions, which are thought to be protective against neurodegeneration.
In diseases such as Alzheimer’s and Parkinson’s, calcium-binding proteins decrease and lead to brain cell death, or neurodegeneration. Scientists believe that by managing calcium levels in the cells, they can slow the aging process and preserve some quality of life.